{"id":75,"date":"2017-06-19T22:41:55","date_gmt":"2017-06-19T20:41:55","guid":{"rendered":"https:\/\/www.pnei.it\/en\/?p=75"},"modified":"2021-02-06T15:18:03","modified_gmt":"2021-02-06T14:18:03","slug":"cancer-cells-not-grow-thin-air","status":"publish","type":"post","link":"https:\/\/www.pnei.it\/en\/2017\/06\/19\/cancer-cells-not-grow-thin-air\/","title":{"rendered":"Cancer cells do not grow out of thin air"},"content":{"rendered":"

\"\"<\/p>\n

Cancer cells rely on the healthy<\/strong> cells that surround them for sustenance. They reroute blood vessels to nourish themselves, and secrete chemicals that scramble immune responses.<\/span><\/p>\n

Recent research shows that cancer cells<\/strong> even recruit and manipulate neurons for their own gain. And not only for brain cancers, but also for prostate cancer, pancreatic cancer, and stomach cancer.<\/span><\/p>\n

Stanford University neuroscientists review how tumors exploit neuronal signals.<\/span><\/p>\n

\u201cThere is no part of the body that is not well innervated,\u201d<\/strong> says Michelle Monje of the Stanford University School of Medicine, \u201cso why shouldn\u2019t cancer cells co-opt them for their own needs?\u201d<\/span><\/p>\n

Cancer treatments cut off blood vessel and nutrient supply routes. Monje believes that it may be possible to block secreted neural growth factors. However, blocking neural activity can be dangerous.<\/span><\/p>\n

Monje argues that, though brains need to be active and functioning, the specific molecular pathways co-opted by tumors could be interrupted.<\/span><\/p>\n

Research into the full molecular details of cancer-nerve partnerships are underway.<\/strong><\/p>\n

The connection between tumor cells and nerves sheds new light on the nature of cancer and possible treatments.<\/span><\/p>\n

Cancers do not grow out of thin air.<\/strong> They have to be in the right microenvironment. Nerve cells and the chemicals they secrete can help cancer cells feel at home.<\/span><\/p>\n

The nervous system in the body extends to each and every part \u00a0of it, providing pathways for the parasitic cancer cells to thrive and spread.<\/span><\/p>\n

References:<\/strong><\/em><\/p>\n

Neuronal Activity in Ontogeny and Oncology<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Cancer cells rely on the healthy cells that surround them for sustenance. 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