Neuroimmune Therapy for the Treatment of Cancer, Autoimmune, and Neurodegenerative Diseases
Recent advances in psycho-neuro-endocrino-immunology suggest that many non-communicable diseases (NCD) originate from disruptions in the cytokine-based immune network (a complex system of communication and regulation among immune cells mediated by cytokines) leading to chronic inflammatory responses.
This persistent low-grade inflammation is attributed to deficiencies in key endogenous anti-inflammatory neuroendocrine systems, including the pineal gland, the endocannabinoid system, and the angiotensin-converting enzyme 2 / angiotensin 1–7 axis.
The administration of pineal methoxyindoles (melatonin, 5-methoxytryptamine), cannabinoids, and angiotensin 1–7 may offer potential therapeutic benefits for NCD, particularly in patients who are unresponsive to conventional treatments.
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